After escaping from Abstergo, Desmond Miles is led to an assassin safe house by Lucy Stillman, Ezio becomes an assassin and vows revenge on those who committed the crime. Desmond Miles is trained to become a
modern-day Assassin through the resurrected
and accesses the genetic memories
of Ezio Auditore da Firenze, his ancestor from 15th Century Renaissance Italy.
After witnessing his father and brothers murdered,
With the help of family and real historical figures,
including Leonardo da Vinci,
Ezio uncovers a greater conspiracy which would lead him directly to
the religious hub of the world and
a Spaniard by the name of Rodrigo Borgia, the man who would become Pope Alexander VI.
memories of ancestor Ezio Auditore da Firenze,
who uncovers a massive Templar conspiracy in Renaissance Italy leading to the new Pope.